BRAC is a global leader in creating large-scale opportunities for the poor. This chapter describes how small farmer innovations are being developed by BRAC Agriculture and Food Security program. In collaboration with the Government and the International Agricultural Research Centers, the program aims to achieve food security and reduce hunger and malnutrition through increased environmentally sustainable agricultural production systems. The research focus is on cereal crops (rice and maize), vegetables and oilseeds. The program is currently implementing several innovative projects targeted at small farmers. BRAC is the largest market player, especially in hybrid seed (rice and maize) production and distribution in Bangladesh, and is gradually expanding to other countries, including Liberia, Sierra Leone, Uganda, Tanzania, South Sudan, Pakistan, Afghanistan, Myanmar, Nepal and Haiti.